Toximed
Rural Chemical Industries (Aust.) Pty Ltd.
TOXIMED is a unique binding and enveloping agent, which actively searches "toxic mould" molecules - even in the chicken's gut. When it locates them, it completely binds and covers the "toxic mould" molecules so that they become harmless.
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View this Toximed product information in English,
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or Chinese languages,
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PDF Format).
The bird is unable to absorb the bound molecules through the gut wall. The inactivated molecules are then passed out in the faeces. Other products simply stop the mycotoxins from growing by interfering with cellular metabolism.
Some Frequently Asked Questions
What is TOXIMED?
When used in the drinking water of poultry at the levels shown on the label, Toximed helps to control the poisonous substances produced by moulds and fungi including Aflatoxin, Cyclopiazonic Acid, Vomitoxin Ochratoxin. T2 & HT2 Toxin, Zearalenone, Penicillium and Fusarium. It also treats disorders caused by mycotoxins in poultry.
What does it contain?
poly[1-(2-oxo-l-pyrroli-dinyl)ethylene 3%
How does it work?
TOXIMED inactivates and detoxifies mycotoxins, restores and normalizes intestinal pH after prolonged antibiotic treatment, assists in controlling diarrhoea caused by diet, errors or food poisoning.
What are the advantages?
- It is 100% soluble
- 100 stable
- It is not necessary to Predilute
- Not necessary to shake the bottle or stir the contents
- TOXIMED is safe with all feed additives, vitamins and minerals
- TOXIMED produces no side efleets
- There is no withdrawal period
| TOXIMED | Competitive Product | |
|---|---|---|
| 1O0% Soluble | Yes | No |
| Stable | Yes | 24 hours only |
| Predilution | No | Yes |
| Stake & Stir | No | Yes |
| Withdrawal Time | Nil | 4 days |
| Sate with Feed Additives | Yes | Yes |
| Side Effects | Nil | Nil |
| Inactivates toxins and detoxifies in the gut | Yes | No |
| Amount used | 100ml/1000L | 100ml/1000L |
How Much Should I Use?
TOXIMED is packed in 1 Litre plastic battles, 10 per carton. Follow the instructions on the Toximed label (below) to
ensure safe and effective usage 
Why dose In the drinking water?
Use in the drinking water is the preferred method as birds will always drink, even when their feed intake is rededuced through stress or disease.
Hot environments depress appetite; for instance birds will eat about 12 % less feed at a temperature of 28 degrees C than at 20 degrees C. In climates where ambient temperatures are higher than 22 degrees C and relative humidity higher than 50%, appetite is depressed (See RCI booklet "How to Understand Heat Stress"). Birds drink more water and eat less. They never stop drinking wen when they are sick. Using drinking water as the medication route ensures the bird is receiving the correct dose all the time.
What are Mycotoxins?
Mycotoxin is the term used to describe a group of secondary metabolites of filamentous fungi sometimes known as "toxic mould". These metaboltles cause a toxic response known as mycotoxicosis. response when eaten by Poultry.
Mycotoxins cause an assorted range of toxic effects because their chemical structures are different from each other. Mainly fungi of the genera Aspergillus, Fusarium, Penicillium, and Claviceps produce them.
More than 250 types have been detected
Poultry feeds are an excellent medium for mould growth, with the risk of fungal growth increasing rapidly when there are high levels of moisture in the air (Relative Humidity). Poultry feed that is stored for more than a few days is a target for mould growth and mycotoxin formation.
The most common type of mycotoxicosis is called aflatoxin, a fungal infection caused by the presence of Aspergillus flavus in the feed. However any other fungal toxins are also found in feed. Another important group of mycotoxins is a chemical which belongs to a class called tricothecenes. There are at There are at least 100 chemicals in this class including T2 and HT2 toxin. These fungi commonly attack grains.
These photos indicate typical mould infestation of corn
This photo shows a typically enlarged liver with spotting clearly visible
This photo shows the gizzard of a newly hatched chick with clear sign of aflatoxin infection
Aflatoxin is implicated in increased susceptibility of broilers to bruising during live haul and processing. It is now well established that when aflatoxin is present, normal events such as catching birds prior to processing or removal from cages at the processing plant may cause rupture of the fragile capillaries. This often leads to downgrading of the cercass.
Breeder hens affected by aflatoxins are known to transfer measurable quantities to both the egg white and yolk. These aflatoxin significantly depress the hatch weight of the chicken and the level of immunity to disease.
The effects of aflatoxin in poultry include:
- Poor growth
- Lower feed conversion
- Increased mortality
- Increased susceptibility to bruising
- Reduced carcass fat
- Impaired blood coagulation
- Impaired kidney function
- Altered immune mechanisms resulting in vaccine failures
- Increased susceptibility to infections
- Decreased ability to resist stress
- Lower egg production
- Lower Hatchbility
- Smaller Eggs
- Fatty liver syndrome
- Liver & kidney lesions
- Decreased semen volume and testes weight
- Abnormal behaviour
- Altered feathering
- Kidney disorders
- Leg & bone problems
- Coccidiosis
- Decreased blood-clotting results in greater downgrading and condemnation of the birds
- Less carcass pigmentation
- Egg yolks are paler
Some of the symptoms of T2 & HT2 TOXINS are:
- Lesions at the edge of the beak
- Abnormal feathering in chicks
- A drastic and sudden drop in egg production
- Eggs with thin shells
- Reduced weight gains
- Mortality
- Reduction in feed consumption
- Severe oral lesions
- Abnormal behaviour
- Altered feathering
- Decreased resistance to pathogens
- Decreased egg production
- Altered immune system
Is Ambient temperature & relative humidity Important?
Two primary climatic danger conditions promote mould growth and the release of mycotoxins
- Relative humidity above 50%
- Ambient temperature above 20 C
When these two conditions occur together, it is very likely mould growth will develop.
Relative humidity plays a critical role in moisture content of feed. A change of RH of 25% to 80% moves the feed from relative safety to danger.
Toxic moulds are resistant to heat and grow rapidly as the temperature rises above 20 degrees C. Even at low temperatures, mould growth continues. Some moulds are capable of producing toxins at temperatures approaching freezing. pH also plays a vital role in mould growth. Most moulds will not grow at a pH of less than 4. Feed mixtures are generally around pH 6-7 Insect infestation and broken and damaged grain also leads to mould growth.
When should mycotoxicosis be suspected?
When disease outbreaks exhibit the following characteristics:
- the cause is not readily identifiable
- the condition is not transmissible
- the problem is associated with certain batches of feed
- treatment with antibiotics has little effect.
How are birds affected?
- Sick birds may drop dead with few signs of illness
- They may be depressed, appear thirsty and pant, but seldom make the gurgling sounds common to other respiratory diseases.
- Dead birds are usually emaciated and their lungs may contain small abscesses about 1 to 2mm in diameter
- Reduction in bodyweight and feed conversion
- Birds show a variety of symptoms such as enlarged lixers spleen and pancreas,repressed bursa and pale combs, shank and bone marrow.
The intestinal tract is characterised by red streaks indicative of a mycotoxicosis problem;
the heart and the liver become enlarged.
Field experience has shown that where aflatoxins are present in birds being treated for diseases that respond to antibiotic treatment the effect of the antibiotic treatment is diminished, resulting in slower recovery and the use of more antibiotics than would normally be required. The most cost effective way to overcome this problem is to treat the aflatoxins first with TOXIMED and then commence the antibiotic treatment.
Contact Us
Find out how using Toximed in the drinking water of your poultry can assist in the control of poisonous substances produced by moulds and fungi and treat disorders caused by mycotoxins in poultry by Contacting Us
| Postal Address | Office Address | Phone & Fax Numbers | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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PO Box 6316 The South Sydney Business Hub Alexandria Sydney, NSW 2015 Australia |
Unit 5, 7-9 Kent Road Mascot Sydney, NSW 2020 Australia |
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Email: Sales & Product Information Web: http://www.rci.com.au
